Be the First to Apply Division Piramal Pharma Solutions Piramal Pharma Solutions is a contract development and manufacturing organization (CDMO), offering end-to-end development and manufacturing solutions across the drug life cycle. We serve our clients through a globally integrated network of facilities in North America, Europe and Asia. This enables us to offer a comprehensive range of services including Drug Discovery Solutions, Process & Pharmaceutical Development services, Clinical Trial Supplies, Commercial supply of APIs and Finished dosage forms. We also offer specialized services like development and manufacture of Highly Potent APIs and Antibody Drug Conjugation. Our capability as an integrated service provider & experience with various technologies enables us to serve Innovator and Generic companies worldwide. For more details, please visit : www.piramalpharmasolutions.com Job Title Senior Research Associate-In-Vitro Job Description To support small molecule drug discovery by developing, optimizing, and validating diverse in vitro assays, including GPCR, kinase, and mechanism of action studies. They will assist in assay automation, execution of high throughput screenings, and data analysis while collaborating with cross functional teams and external stakeholders. Strong technical knowledge and ability to work in a dynamic, fast paced environment are essential. Understand and implement new experiments as per Customer requirement to answer in vitro Biology query to support small molecule drug discovery and development projects from various global customers. Attend Customer call to understand the requirement, propose study design and costing details to your reporting manager. Develop, optimize, and validate biophysical, biochemical, and cell based assay platforms for the hit identification, ead optimization and functional characterization of small molecules. Ensure to coach your team member during the above process. Robust and high quality assays with efficient use of automation and instrumentation will be an advantage. Work with different biological assays such as GPCR, Kinase and MOA studies, offering integrated drug discovery support alongside chemistry and support functions for multiple client based projects. Help to develop diverse In Vitro target/mechanism assays, amenable for high throughput screening, surrounding different key cellular processes and signal transduction pathways. Strong experience of working with small molecule drug discovery from a CRO/Drug Discovery company with an ability to efficiently handle time bound and service based projects. Should have strong technical knowledge with exceptional attention to detail. Understanding of basic molecular biology, cell biology and biochemistry experiments will be an advantage. Broad research experience in cell free and cell based assay development using mentioned technology/platform viz. DELFIA® (Dissociation Enhanced Lanthanide Fluorescent Immunoassay), Fluorescence, Fluorescence Polarisation (FP), Luminescence, TRF, TR FRET & HTRF, Alpha Screen assays, Nano BRET, Electrochemiluminescence (ECL), Flow Cytometry, FLIPR, High content imaging, Live Cell Analysis. Knowledge on Surface Plasmon Resonance (SPR) technology will be an advantage. Experienced in development and validation of In Vitro models for diverse diseases especially related to oncology, inflammation, immunology, neurology, metabolic disease etc. Experience working with board target classes e.g., enzymes, GPCRs, transporters, ion channels, surface receptors, etc. across different therapeutic areas. Execute program objectives, meticulously record experimental data and observations on a timely basis in acceptable format, prepare technical reports, summaries, and quantitative and qualitative analyses in written form. Work both independently and as part of a collaborative team in multiple geographies to design, plan and execute experiments that support research activities and project goals. Clearly communicate the status of projects, challenges, results, and proposed paths forward across internal and external stakeholders. Participate in cross functional team activities, regularly add value to research projects through creative ideas. Demonstrate excellent oral and written communication skills. Work well within a fast paced, dynamic, results and team oriented start up environment. Open to miniaturize the assay from 96WP to 384WP to 1536WP format for both cell free and cell based assays.